Xefo is fattening? What To Do, How To Take And Side Effects
Have you ever heard of a drug called Xefo? Can you tell what the remedy is for? Well, according to information from the package leaflet provided by the National Agency of Sanitary Surveillance (Anvisa), it is a non-hormonal and antirheumatic anti-inflammatory drug.
According to the document, it is indicated for the treatment of acute and chronic low back pain, postoperative pain and joint pain and inflammation, which involves diseases such as rheumatoid arthritis and osteoarthritis.
Its commercialization is allowed only upon presentation of the prescription.
Xefo gets fat?
To understand whether or not Xeph is fattening, we need to first look at the information contained in his leaflet. And, according to the document, we can not say that this happens, at least not directly, since the party listing the side effects of the drug does not mention anything like gain or gain in weight or increase in appetite.
What appears among the common adverse reactions, ie between 1% and 10% of patients using the drug, are swelling and fluid retention, a condition known to cause swelling.
When the body becomes swollen, it appears to be brighter and you may get the impression of weight gain. But that does not mean there was an increase in body fat. In addition, what the Bull indicates is that these effects are not observed by all - only by a portion of the users.
So, what we can affirm is not that Xefo gets fat, but that can leave the body swollen. However, if you find that you gained weight when using the medicine, seek the doctor responsible for your treatment so that it determines whether it is only swelling or even weight gain, what may have caused the problem, and how to handle it that.
Xefo side effects
According to the package leaflet provided by Anvisa, the drug may cause the following side effects:
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- Small increase in the risk of heart attack or stroke, which is higher with higher doses and prolonged treatments;
- Difficulty getting pregnant;
- Visual disturbances such as blurred vision, altered color vision, defective visual field, black spots in the field of vision, reduced vision, double vision, iris inflammation and visual nerve inflammation;
- Mild and transient headache;
- Fluid retention;
- Abdominal pain;
- Stomatitis - inflammation in the mouth;
- Vomiting, including with blood;
- Cardiac insufficiency;
- Chest pain;
- Vasculitis - inflammation of the vascular wall;
- Asthma attack;
- Gastric ulcer;
- Duodenal ulcer;
- Ulcer in the mouth;
- Significant alteration of liver exams;
- Erythema - redness on the skin;
- Sensitivity to light;
- Joint pain;
- Aseptic meningitis - virus-induced meningitis, especially in patients with autoimmune disease such as systemic lupus erythematosus;
- Hemolytic anemia (abnormal destruction of red blood cells) and aplastic (decreased production of blood cells);
- Reduction in blood cell count;
- Bronchospasm - difficulty breathing due to contraction of the bronchi;
- Anaphylactoid reaction;
- Hyponatremia - decreased sodium levels;
- Inability to concentrate;
- Cognitive dysfunction;
- Paresthesia - tingling sensation;
- Abnormal taste sensation;
- Attention Disorder;
- Hyperkinesia - excessive abnormal movements;
- Hypoaesthesia - decreased sensitivity to touch;
- Black stools;
- Inflammation of the esophagus - esophagitis;
- Gastroesophageal reflux;
- Difficulty in swallowing;
- Peptic ulcer;
- Gastrointestinal bleeding;
- Bleeding gums;
- Skin inflammation;
- Skin disorder;
- Rash with small spots and lumps;
- Hyperhidrosis - excessive sweating;
- Bone pain;
- Back pain;
- Muscle cramp;
- Muscle weakness;
- Synovitis - inflammation of joint lining tissue;
- Renal insufficiency in patients not dependent on renal prostaglandin to maintain renal flow;
- Nephrotic syndrome - severe kidney disease with protein release in the urine;
- Interstitial nephritis - inflammation of the kidneys;
- Papillary necrosis - kidney disease with tissue death;
- Membranous nephropathy - kidney disease;
- Severe liver reactions, such as jaundice and fatal hepatitis;
- Eczema - acute or chronic inflammation of the skin, according to Your Health;
- Skin changes;
- Psoriasis - inflammatory skin disease;
- Purple - small red patches on the skin;
- Severe skin diseases such as erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis;
- Hair loss.
The package leaflet states that if the user experiences any unusual abdominal symptoms such as abdominal bleeding, skin reactions such as skin rash, mucosal damage or other signs of hypersensitivity / allergic reaction, he or she should stop using the medicine and seek help your doctor immediately.
The same guidance applies to cases where the patient experiences shortness of breath, chest pain, swelling, increased swelling of the ankle, severe or continuous stomach pain, black stools, yellowing of the skin and eyes (jaundice), Stevens syndrome -Johnson (fever, blistering or inflammation especially in the feet, hands and mouth area) and, exceptionally, serious skin infection in cases where he has chickenpox.
Similarly, the document warns that when suffering from other undesirable reactions with Xefo, the patient should quickly seek the doctor responsible for their treatment to know how to proceed.
Contraindications and precautions with Xefo
The medicine can not be used by people who are hypersensitive to lornoxicam or any of the ingredients of the drug formulation and are hypersensitive, presenting with symptoms such as asthma, rhinitis, angioedema (swelling in the deepest layer of the skin), or urticaria, non-steroidal anti-inflammatory drugs, including acetylsalicylic acid.
Those who suffer from gastrointestinal bleeding, cerebrovascular haemorrhage (hemorrhagic stroke), and other bleeding disorders should also not use the medicine. Xefo is also contraindicated for people with a history of gastrointestinal bleeding or perforation associated with prior use of non-steroidal anti-inflammatory drugs.
Children and adolescents under 18 years of age and women in the last three months of pregnancy should not use Xefo. The same applies to those who are in the first six months of pregnancy or breastfeeding, unless there is medical advice.
People with peptic ulcer or history of recurrent peptic ulcer and individuals with thrombocytopenia (decreased number of elements in the blood, linked to blood clotting) are other groups that can not use the remedy.
Patients with renal insufficiency, history of hypertension and / or heart failure with fluid retention and edema (swelling), ulcerative colitis (inflammation of the intestinal colon) or Chron's disease (inflammatory bowel condition) require special care when being treated with Xefo and use of the medication should only occur after a careful evaluation of the risks and benefits made by the doctor.
Users who have blood clotting disorder, are elderly, have liver failure, or who have been taking the drug for more than three months need to be monitored by their doctor through frequent laboratory tests.
Anyone who has or has ever had bronchial asthma should tell their doctor about this when receiving the medicine. The same recommendation is for those who suffer from intolerance to some sugars.
People with heart problems, previous stroke, or conditions that can lead to such problems - such as high blood pressure, diabetes, high cholesterol, or being a smoker - should also report the issue to the doctor for Xefo treatment to be discussed.
It is advisable to avoid the medicine during a chickenpox and, since it can compromise fertility, women who are trying to become pregnant or have problems getting pregnant should inform the doctor about the situation when they receive the Xefo prescription.
Users who experience side effects such as dizziness, drowsiness, visual disturbances and fatigue when using the medicine can not drive vehicles or operate machines.
If the patient is being treated with any other substance or medication, he or she should also inform the doctor about this so that the practitioner can check for risks of interactions.
The information is from the package leaflet provided by Anvisa.
How to take - Dosage
First of all, who should set the dosage of the drug, the duration of treatment and how often it should be taken per day is the doctor.Self-medication poses serious risks, and as explained in the Xefo's package leaflet by Anvisa, larger doses and longer treatment periods increase the small increase in the risk of heart attack and myocardial infarction.
Thus, nothing to take a higher dosage than the one recommended by the doctor or for a longer time.
The package leaflet also warns that the medicine should be taken with a glass of water before, during or after meals, as directed by the doctor. However, the document also states that the use of the drug concomitant with food consumption may cause the absorption of the drug to be decreased.
According to the package leaflet, the dose is usually 8 mg to a maximum of 16 mg divided into two doses per day, but you should not "choose" your dosage, but take it according to what your doctor has determined .
In cases in which the medication is forgotten, the document states that a double dose should not be taken to compensate for the tablet that has been forgotten.
Price of Xefo
It is possible to find the medicine for sale for a price range from R $ 23.90 to R $ 30.82 - in the case of packaging with 30 coated tablets - or from R $ 15.97 to R $ 20.60 - if it is the package with 20 coated tablets.
However, keep in mind that you can still find different values according to the establishment and the city in which the medication is purchased.